Nuvonis Avian Cell Line
Nuvonis has developed a continuous avian cell line from quails, as these lack most of the endogenous retroviral sequences detectable in chicken families. For immortalization and development of the cell line, no viral sequences and no foreign genes were introduced. Therefore, the cell line is not regarded as being genetically modified (GMO).
The avian cell banks are suitable for production of a variety of viruses. Avian cell lines can be used to replace Chicken Embryo Fibroblasts (CEF) or cultivation in embryonated hen’s eggs.
Avian cell line characteristics
Nuvonis avian cells grow in serum-free/animal component free medium that is commercially available.
Both, adherent cells and cells growing in suspension are available.
The cell banks are well characterized and have been tested, e.g. for Sterility, Mycoplasma, Extraneous agents, tumorigenicity etc.
Quail cell bank ampoules can be provided to clients at low cost (R&D fee) after signature of CDA and MTA.
Nuvonis provides protocols for cell thawing and expansion and technical support.
GMP production of MCB and WCB planned